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High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions

Dominic Hoepfner1*+, Stephen B. Helliwell1+, Heather Sadlish1+, Sven Schuierer1, Ireos Filipuzzi1, Sophie Brachat1, Bhupinder Bhullar1, Uwe Plikat1, Yann Abraham1, Marc Altorfer1, Thomas Aust1, Lukas Baeriswyl1, Raffaele Cerino1, Lena Chang1, David Estoppey1, Juerg Eichenberger1, Mathias Frederiksen1, Nicole Hartmann1, Annika Hohendahl1, Britta Knapp1, Philipp Krastel1, Nicolas Melin1, Florian Nigsch1, Edward J. Oakeley1, Virginie Petitjean1, Frank Petersen1, Ralph Riedl1, Esther K. Schmitt1, Frank Staedtler1, Christian Studer1, John A. Tallarico1, Stefan Wetzel1, Mark C. Fishman2, Jeffery A. Porter2, N. Rao Movva1

Affiliations:

Published in Microbiological Research 169 (2014) pp. 107-120

A detailed description of the applied methodologies and tested compounds can be found at the link above. At the linked site you can also download the supplemental material for further analysis. Alternatively, the underlying data tables and supplemental materials mentioned in the publication can be downloaded from http://doi.org/10.5061/dryad.v5m8v



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Please contact the corresponding author, dominic.hoepfner@novartis.com, if you have any questions. Thank you.